Increased epithelial stem cell traits in advanced endometrial endometrioid carcinoma
نویسندگان
چکیده
منابع مشابه
Tumor progression, metastasis, and modulators of epithelial-mesenchymal transition in endometrioid endometrial carcinoma: an update.
Endometrioid endometrial carcinoma (EEC), also known as type 1 endometrial cancer (EC), accounts for over 70-80% of all cases that are usually associated with estrogen stimulation and often develops in a background of atypical endometrial hyperplasia. The increased incidence of EC is mainly confined to this type of cancer. Most EEC patients present at an early stage and generally have a favorab...
متن کاملIMP3 distinguishes uterine serous carcinoma from endometrial endometrioid adenocarcinoma.
Differentiating uterine serous carcinoma (USC) from endometrioid adenocarcinoma (EAC) could be problematic, especially in high-grade EACs and tumors exhibiting architectural variations. To address this issue, we evaluated 103 endometrial carcinoma cases using 4 immunomarkers, beta-catenin, IMP3, PTEN, and p53. Cases included 31 USCs, 57 EACs, and 15 mixed EAC-USCs. Of 31 USCs and 57 EACs, 8 and...
متن کاملTumor angiogenesis, macrophages and mast cell microdensities in endometrioid endometrial carcinoma
The present study aimed to observe and compare the values of microvessel density (MVD), mast cell microdensity (McMD) and macrophage microdensity (MphMD) in intratumoral areas compared with the advancing edges, and to assess any correlations between these values and the degree and stage of the neoplasia. The cases of 52 patients who were diagnosed with endometrial carcinoma between 2003 and 201...
متن کاملEndometrioid Endometrial Carcinoma of the Urinary Bladder - A Diagnostic Challenge
Endometriosis of the urinary bladder is uncommon and malignant transformation of bladder endometriosis is extremely rare. These malignant tumours can cause problems in differential diagnosis with bladder tumours. This report illustrates an interesting case of endometrioid adenocarcinoma of the urinary bladder, which illustrates the difficulties in diagnosis and the importance of morphology and ...
متن کاملPINCH protein expression in normal endometrium, atypical endometrial hyperplasia and endometrioid endometrial carcinoma.
BACKGROUND Particularly interesting new cysteine-histidine rich protein (PINCH), as an adapter protein of the LIM family for signal transduction in the integrin and growth factor pathway, is upregulated in the stroma of several common types of cancers and involved in promoting tumor progression. In the present study, we examined PINCH expression in normal endometrium, atypical endometrial hyper...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Genomics
سال: 2009
ISSN: 1471-2164
DOI: 10.1186/1471-2164-10-613